The study first evaluates the strategies of the Sustainable Development Goals (SDGs), and the report of the United Nations Business and Sustainable Development Committee in 2017, “Better Business, Better World”. Connecting with Green Chemistry 12 key principles of chemical industry, the international toxic chemical management sould be promoted to the safer and environmental friendly chemicals. The development of chemical management and toxic chemical substances including integrated management system, regulation, and framework in the United States, the European Union, Canada, Germany, Japan, South Korea, and China were revied. Several chemical safety alternative assessment systema around the world were also procided. The safety chemical substitution assessment criteria was proposed to evaluate safer chemical alternatives, including five cases of chemical substitution assessment cases in the academia area and three cases in the industry. In addition, to improve the promotion of toxic chemical alternatives, we also invited related experts from government, industries and academy to hold Ad Hoc committees on 11th July. The future works are (i) to finish the list of safer chemical alternatives (at least 10 chemicals), (ii) to organize a second Ad Hoc committee for integrated chemical management, and (iii) to conduct the educational materials of safer chemical alternatives and Green Chemistry principles for the industry. And on August 22, the project team attended 2019 Taiwan Chemical Industry Summit, focusing on "New Vision for New Sustainable Development of Green Chemistry Technology". The main theme were "Best Practices" and "Technical Achievement". From October 1st to 2nd, project team assisted in handling the "International Symposium on Comprehensive and Innovative Solutions for Circular Economy", invited experts and scholars working on issues in the field of circular economy at home and abroad, analyzed international development trends, and provided new solutions for domestic industry, government, academic research Exchange with ideas, strengthen the attention of all sectors of the industry, government, academia, and research to the circular economy, and discuss the four themes of governance and guidance, sustainable finance, sustainable processes, and business models. In addition, the "Green Chemistry and Poisonous Chemicals Management Industry Symposium" was held on November 27. Relevant key conclusions include the establishment of a link between the government and the industry to deepen the promotion of policies on poisoning reduction and management. Based on the aformentioned information for revelent references and ad hoc committee’s suggestions, the summeries are included: (1) to investigate the status of toxic chemical substance management around the world, including the declaration and management of toxic chemical substances system, legal basis, and regulatory framework; and to analyze and evaluate international assessment methods for promoting alternative chemicals; (2) to search the information platform on international green chemistry promotion, toxi substances assessment tools, and to propose a preliminary list of priority promotion of green chemistry and safe substitution; (3) to develop a list of domestic processes and recommendations for the promotion of alternative chemicals and a comprehensive evaluation flowchar for alternative chemicals.

Green Chemistry Principles, Toxic Chemical Sustances Management, Safer Alternatives